Aquero
Company, founded in 2002, provides research and development on a contract basis in the area of proteins, polyamino acids,
polysaccharides, lipids and related chemical materials. Aquero also conducts early commercialization activities such
as writing, filing and prosecuting patent applications worldwide, meeting with investors and customers of client companies,
and providing prototype samples for pre-commercial evaluation.
Our current projects focus
on novel and useful compositions of 100% human milk. These compositions are made via our own novel and proprietary methods that are far more efficient and cost-effective
compared to conventional manufacturing processes of human milk products. The products formulated from these compositions
are commercially sterile, shelf stable, and fully "competent".
This means they retain all of the multitude of bioactive molecules
like immunoglobulins and growth substances in fully active forms. Significantly, the products can be shipped and kept
at room temperature without decomposition for extended periods of time.
The products are available in both
powdered and liquid forms. The emphasis to date has been on human milk, but the patent filings include all mammalian
milk. A lot more information about these projects is available within the human milk tab on the left.
Such products did not exist before. Fresh human milk and other mammalian milks are wonderfully
alive when freshly expressed. They are replete with many thousands of bioactive molecules like enzymes, immunoglobulins,
and growth factors, plus robust populations of both mammalian and microbial cells. However, the milks are not stable.
They begin to metabolise their own content right away upon being expressed by the mother. The best option is for
the infant to be fed directly by the mother. If this is not feasible or even possible, the freshly expressed milks can be refrigerated for a few days or frozen
for a longer period before use.
But for commercial purposes, the milks are subjected
to heat-based techniques that while partially or completely inactivating the microbes and other cells, thus stabilizing the
milk. In the process, the bioactive components are also compromised. Depending on the more moderate heat levels
of pasteurization at around 65 oC, or in the extreme of very high temperature "retort" at around 125
oC and higher, the milk ranges from partial to complete inactivation of the biocomponents.
The retort method is used to make the products shelf-stable, which is convenient and a good marketing strategy,
but can result in a product that is compromised nutritionally and immunologically.
We provide samples of novel chemical materials up to the kilogram level. We also
offer technologies for license or sale. We have worked with both large and small companies worldwide in a number industries
and commercial sectors.
Brief summaries of some of our earlier projects and the sponsoring companies are provided
below.
Procter and Gamble.
Additives for personal care including antitartar agents for Crest, dispersants
for Tide and Cheer, superabsorbents for Pampers and related products.
Rohm and Haas (later acquired by Dow). Antiscaling
agents and corrosion inhibitors for water treatment, dispersants for detergents, and polymeric materials for personal care
applications.
Bayer AG. Biopolymer additives
for green detergents and related products. The detergent based projects developed into businesses that produce 10,000's
of metric tons of polymers per year.
BASF Master Builders.
Construction chemicals for improved performance of cement based materials and other related materials
Stepan Company. Agricultural agents for erosion
control and water penetration, plus a number of other applications.
Filterboxx
Water and Environmental. Novel chemicals and chemical treatments for produced water clarification in
the oil sands region of Canada.
Gibson
Energy. Water treatment chemicals, methods of water clarification, and complete on-site treatment systems
for disposal of process water at deep-well disposal sites in Alberta, Canada. We designed, built, installed, commissioned,
and provided initial operations for a hard-piped and permanently wired system on the ground in western, central Alberta.
We also designed a mobile, truck-mounted system for treating frac waters and other process waters.
The collective
oilfield projects produced chemistries, methodologies, and systems that have been adopted by O&G companies and related
water-service companies throughout the world.
We have also founded and worked with several start-ups including Folia, Inc. (precursor to Aquero);
Innovium, Inc.; Aquial, LLC; Aquero Canada, LLC; and Aquero Process Water Systems, LLC.
The common thread of all of the projects has to do
with water and substances dissolved, emulsified, or suspended in water. For example,
the sponsor and customers may want the aqueous solution to be completely clarified, or they may want some substances removed
and some retained, or they may want the aqueous product to be built in a completely novel way from water and both biological
and mineral components.
Aquero's patented technologies include novel compositions of
matter, methods of their synthesis, their uses, commercial manufacturing processes, and proprietary capital equipment that
is designed specifically to optimize performance. We have been awarded over 100 national and international patents and
have several patents pending. All have been licensed at one time or another.
Prior to focusing on work solely in the private sector, we published over 100 professional papers in the peer-reviewed
literature. We also participated in many national and international meetings as speakers, invited speakers, keynote
speakers and organizers.
Most of that work was funded through 48 grants by various federal
and state agencies including the US National Science Foundation, the US National Institutes of Health, the National Institute
of Environmental Health Sciences, the NIH Study Section on Tissue Engineering, the US National Oceanic and Atmospheric Association,
the US Office of Naval Research, the US Office of Technology Assessment, the US Environmental Protection Agency, the Mississippi
Alabama Sea Grant Association, and the Alabama Research Institute.
Agriculture Projects